3. Pathophysiology and treatment of malignant glioma : Chemotherapy (A2 Up-date on pathophysiology and treatment strategy of malignant glioma)
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چکیده
منابع مشابه
Head's up on the treatment of malignant glioma patients.
P rimary brain tumors are rare. As a consequence , oncology nurses may not be familiar with the spectrum of diagnoses within this group and the impact that diagnosis has on prognosis and treatment of these tumors. Although typically associated with a poor prognosis, recent advances have been made in the diagnosis and treatment for these tumors that generates great optimism for continued improve...
متن کاملBiology and Treatment of Malignant Glioma
Gliomas are rare compared to cancers of the breast, lung, or colon, but few malignancies are more devastating. While no therapeutic breakthroughs have occurred, the treatment of glioma is improving. Surgical care is improving. Magnetic resonance imaging and intraoperative mapping studies are leading to safer, more complete resections. With scan-guided stereotactic biopsy, unresectable tumors ca...
متن کاملTemozolomide and treatment of malignant glioma.
Malignant gliomas (glioblastoma multiforme and anaplastic astrocytoma) occur more frequently than other types of primary central nervous system tumors, having a combined incidence of 5-8/100,000 population. Even with aggressive treatment using surgery, radiation, and chemotherapy, median reported survival is less than 1 year. Temozolomide, a new drug, has shown promise in treating malignant gli...
متن کاملBiology and treatment of malignant glioma.
A large number of oncogenes have been identified as aberrant in gliomas, but only the erbB oncogene (gene encoding the epidermal growth factor receptor [EGFR]) is amplified in an appreciable number. The loss or mutation of tumor-suppressor genes located on different autosomes may be associated with progression of malignant gliomas. The p53 tumor-suppressor gene (located on chromosome 17) is fre...
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ژورنال
عنوان ژورنال: Japanese Journal of Neurosurgery
سال: 2004
ISSN: 0917-950X,2187-3100
DOI: 10.7887/jcns.13.280_3